Coronavirus disease (COVID-19) infection has caused morbidity and mortality at an unprecedented scale [1]. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel beta coronavirus responsible for new respiratory infections with mild-to-severe presentations in humans. At the beginning of the pandemic, major attention was directed to investigate the acute effect of COVID-19, as well as to identify potential therapeutic and preventive strategies to control the virus spread. More than a year after the first case was described in Wuhan, China, the scientific community faces the long-term impact of this disease. Indeed, subjects affected by COVID-19 may experience various symptoms, such as fatigue, weakness, dyspnea, physical deconditioning lasting more than one month [2]. This condition, recently defined as post-acute COVID-19 syndrome, is characterized by persistent symptoms and/or delayed or long-term complications beyond 4 weeks from the onset symptoms [2]. …