Journal of Exercise & Organ Cross Talk
Journal of Eexercise & Organ Cross Talk

A Single Daily 10-Second Sprint Snack Can Improve Left Ventricular Redox Balance in Male Wistar Rats

Articles in Press

Document Type : Original Article

Authors

Fatemeh Pilehvar 1
Mohammad Rahmani 2
Ali Samadi 2

1 MSc in Exercise Physiology, Shahed University, Tehran, Iran

2 Department of Physical Education and Sport Sciences, Shahed University, Tehran, Iran.

10.22122/jeoct.2026.591781.1218
Abstract
Introduction: Exercise snacks are time-efficient physical-activity strategies, but the cardiac redox effects of a single ultra-short daily sprint are unknown. This study examined whether one daily 10-second sprint snack modifies left ventricular oxidant-antioxidant balance in male Wistar rats.

Methods: Twelve male Wistar rats were randomized to control (CO, n = 6) and single daily sprint snack (DSS, n = 6) groups. After treadmill familiarization and maximal treadmill running speed assessment, the DSS group performed one daily sprint, six days per week, for eight weeks. Forty-eight hours after the final session, left ventricular tissue was analyzed for malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx), and total antioxidant capacity (TAC).

Results: Compared with CO, DSS reduced MDA (p = 0.004) and increased SOD (p = 0.011), GPx (p = 0.010), and TAC (p < 0.001). All four outcomes remained statistically significant in a post hoc Holm sensitivity analysis.

Conclusion: A single daily 10-second sprint snack favorably modified left ventricular redox biomarkers in male Wistar rats. These findings support a minimal-volume model of redox adaptation, although effects on exercise performance, cardiac structure, and cardiac function remain to be established.

Keywords

Sprint snack
Lipid peroxidation
Antioxidant capacity
Left ventricle
Subjects
Journal of Exercise & Organ Cross Talk

Articles in Press, Accepted Manuscript
Available Online from 19 September 2026

  • Receive Date 14 July 2026
  • Revise Date 17 September 2026
  • Accept Date 19 September 2026

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