Journal of Exercise & Organ Cross Talk
Journal of Eexercise & Organ Cross Talk

Smart running as a low‑cost health‑promoting strategy: The HamGhadam (step-for-good) workplace physical activity program at Gol-Gohar Sirjan club

Articles in Press

Document Type : Review Articles

Authors

Hosein Abedini Parizi 1
Ali Pahshabadi 2
Aniss Khorasani 3
Khatere Pour Jafarabadi 4
Asqar Nikravesh 5
Amir Hossein Ahmadi Hekmatikar 6

1 Sports Science Committee, Gol Gohar cultural and sports club, Sirjan, Iran.

2 Department of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.and, Sports Science Committee, Gol Gohar cultural and sports club, Sirjan, Iran.

3 PhD Candidate, Department of Sport Biomechanics, Faculty of Physical Education and Sport Science, Shahid Bahonar University of Kerman, Iran and Sports Scientific Committee, Gol Gohar cultural and Sports club, Sirjan, Iran.

4 Sports Director, Golgah Sports Cultural Club, Staff and Family and Sports Science Committee, Gol Gohar cultural and sports club, Sirjan, Iran.

5 HSE Manager, Gol Gohar Sirjan F.C. and Sports Science Committee, Gol Gohar cultural and sports club, Sirjan, Iran.

6 Department of Physical Education and Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran 10600, Iran Sports Science Committee, Gol Gohar cultural and sports club, Sirjan, Iran.

10.22122/jeoct.2026.573460.1189
Abstract
Physical inactivity is a major global determinant of non-communicable diseases, particularly in industrial and occupational environments where structural and environmental barriers limit regular engagement in physical activity. Although the health benefits of aerobic exercise are well established, less attention has been given to the physiological specificity of exercise intensity and its translation into feasible health promotion strategies in real world settings. Current evidence indicates that moderate intensity running (approximately 50–70% heart rate reserve, 46–63% VO₂max, or Borg RPE 12–14) induces coordinated multisystem signaling responses that support metabolic regulation and inflammatory balance. These responses include favorable modulation of myokines, adipokines, neurotrophic factors, and immunoregulatory mediators involved in metabolic homeostasis. Particular attention is given to the context dependent role of interleukin 6, highlighting the distinction between its transient exercises induced signaling effects and the chronic elevations associated with metabolic and inflammatory diseases. In addition to mechanistic insights, this review discusses translational considerations such as adherence, safety, and long term sustainability of moderate intensity running programs in occupational populations. The HamGhadam (Step for Good) initiative implemented by Gol Gohar Mining and Industrial Company is presented as a descriptive workplace case example illustrating how structured physical activity programs can be incorporated into corporate wellness initiatives. The manuscript does not claim empirical validation of the program’s effectiveness but highlights its potential as a practical model for workplace health promotion. Overall, smart running is framed as a biologically efficient and potentially scalable strategy that conceptually bridges molecular exercise biology with population level physical activity promotion.

What is already known on this subject?

Physical inactivity is a major global determinant of non-communicable diseases, particularly in industrial and occupational settings where structural and environmental barriers limit regular physical activity. Although the health benefits of aerobic exercise are well established, less attention has been paid to the physiological specificity of exercise intensity and its translation into feasible health-promotion strategies in real-world contexts. Current evidence shows that moderate-intensity running elicits coordinated multisystem signaling responses that support metabolic regulation and inflammatory balance. In addition, physical inactivity and sedentary behavior are consistently associated with increased risk of chronic disease, premature mortality, and reduced functional capacity, whereas higher levels of physical activity and cardiorespiratory fitness are linked to lower morbidity and mortality.

 

What this study adds?

This narrative review introduces the concept of “smart running” as a biologically informed and potentially scalable strategy for workplace health promotion. The study integrates current evidence on moderate-intensity running with mechanistic insights related to myokines, adipokines, neurotrophic factors, and inflammatory regulation, particularly the context-dependent role of interleukin-6. In addition, the HamGhadam (Step for Good) initiative is presented as a descriptive workplace case example illustrating how structured physical-activity programs may be incorporated into occupational wellness settings. The manuscript also highlights practical considerations related to feasibility, adherence, safety, and long-term sustainability of workplace running programs.

Keywords

Hamqadam
Physical activity
Disease
Golgohar Sirjan
Subjects

Acknowledgements

The authors acknowledge the Gol Gohar Club for providing background information regarding the HamGhadam (Step for Good) initiative. The intellectual property of the HamGhadam platform belongs to the Gol Gohar Club of Sirjan. The concept of this article was originally proposed by the Deputy of Sports Affairs of Gol Gohar Sirjan Club, and the HamGhadam initiative was developed as an idea for Gol Gohar Sirjan Club.

Funding

This research received no direct financial support. However, the HamGhadam (Step for Good) initiative, which is discussed as a case example, was supported in kind by the Gol Gohar Club through provision of platform access and contextual information.

Data availability

Data will be made available upon reasonable request.

Compliance with ethical standards

Conflict of interest The authors were involved in the conceptual development and/or scientific advisory aspects of the HamGhadam program, which is presented in this manuscript as a locally adapted workplace physical activity intervention rather than as a commercial product or digital platform. The authors state that the analyses and interpretations are independent and do not constitute an endorsement of any commercial entity. Nevertheless, to ensure full transparency, this involvement is disclosed as a potential non-financial conflict of interest.

Ethical approval Review article

Informed consent Performed. 

Author contributions 

Conceptualization and development of the smart running framework: A.A.H. and H.A.P.; Scientific input and contextual analysis related to the HamGhadam case example: A.A.H.; Writing—original draft preparation: A.A.H., A.KH., and KH.P.; Review and editing: all authors. All authors have read and approved the final manuscript.

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Journal of Exercise & Organ Cross Talk

Articles in Press, Accepted Manuscript
Available Online from 10 May 2026

  • Receive Date 01 February 2026
  • Revise Date 02 May 2026
  • Accept Date 10 May 2026

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