Journal of Exercise & Organ Cross Talk
Journal of Eexercise & Organ Cross Talk

Effect of a session of repeated sprint training (RST) on serum adropin levels, inflammatory, and coagulation factors in healthy young men

Document Type : Original Article

Authors

Seyed Sarmad Zahmatkeshan
Hamid Rajabi
Mohammad Amin Farhani
Azam Ahmadi

Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Kharazmi University, Tehran, Iran.

https://doi.org/10.22122/jeoct.2025.493686.1134
Abstract
Intense and high-speed intermittent training is recognized as an effective method for achieving rapid and extensive physiological and functional adaptations. However, it is important to consider that a single session of such exercises can exert significant physiological stress, potentially leading to adverse effects. Therefore, this study investigated the effects of a repeated sprint training (RSA) session on serum adropin, inflammatory, and blood coagulation factors. Ten healthy young men (age: 23.60 ± 2.01 years, weight: 68.60 ± 7.21 kg, body mass index: 22.00 ± 2.10 kg/m2) participated in this study. Blood samples were collected before, immediately after, and 20 minutes following the exercise protocol for measuring of adropin protein, fibrinogen, CRP, WBC, RBC, Hgb, and Hct levels. The exercise protocol consisted of 20 repetitions of different running speeds in a distance of 20 meters, with a 20-second rest period after each repetition (20*20*20). A significant increase in adropin, fibrinogen, WBCs, RBC, Hgb and, Hct levels was observed immediately after the exercise (p < 0.05). But only Adropin levels remained significantly higher than before the exercise after 20 minutes following the exercise. Therefore, even after exercise, adropin levels can remain elevated, allowing for the continuation of its positive effects. However, it is important to note that the increase in fibrinogen levels may require further investigation, particularly in relation to the use of anticoagulant agents. Therefore, when considering the implementation of these intense activities for inactive individuals, it is crucial to exercise caution and carefully assess the potential risks involved.

What is already known on this subject?

Repeated Sprint Training (RST) has been studied extensively for its effects on physical fitness like maximal oxygen consumption, repeated-sprint ability, Countermovement jump, Change of direction. Also, Studies have shown that RST can lead to an increase in inflammatory markers such as interleukin-6 (IL-6) post-exercise and RST can induce oxidative stress, indicated by increased levels of markers like serum myoglobin and lipid peroxidation.

 

What this study adds?

Specific studies on the effect of RST on serum adropin levels are scarce. Also, there is limited research specifically focusing on the effects of RST on coagulation factors.

Keywords

Adropin
Intensive exercise training
Inflammation
Blood coagulation

Subjects

Acknowledgements

We wish to thank our participants for their time and effort.

Funding

No sources of funding were sought or awarded for this study.

Compliance with ethical standards

Conflict of interest The authors declare that they have no conflict of interest.

Ethical approval All procedures in this study were carried out under the Helsinki Statement regarding human research. The proposal for this project was presented to the Ethics Committee of the Research Institute of Physical Education and Sports Sciences of Iran and approved (ethics code SSRI.REC-2307-2323).

Informed consent Participants signed an informed consent form prior to participation in the study.

Author contributions

Conceptualization: S.S.Z., H.R., M.A.F.; Methodology: A.A., H.A., H.R.; Software: A.A.; Validation: H.R., Formal analysis; Investigation: S.S.Z.; Resources: M.A.F.; Data curation: H.R.; Writing - original draft: A.A.; Writing – review & editing: H.R.; Visualization: M.M.A.; Supervision: H.R. Project administration: H.R.; Funding acquisition: A.A.

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Journal of Exercise & Organ Cross Talk
Volume 4, Issue 3
Summer 2024
Pages 166-176

  • Receive Date 13 July 2024
  • Revise Date 06 September 2024
  • Accept Date 07 September 2024

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