What is axoplasmic transport? Considering the role of exercise training: A mini review

Document Type : Review Articles


PHD Student of Exercise Physiology, Department of Sport Sciences, Shiraz University, Shiraz, Iran.


Like other cells in the body, nerve cells need many proteins and substances to maintain homeostasis. As we know, the transcription and translation of proteins and necessary cellular substances occurs in the cell nucleus. The nucleus of nerve cell is located in the cell body. Another part of the nerve cell is “Axon”, which has a long structure. Even in some nerve cells axon’s length reaches up to 1000 mm. On the other hand, all parts of the neuron need substances and proteins synthesized in nucleus locating in the cell body. Therefore, a mechanism is necessary to express the movement of materials from nucleus along the axon. The movement of materials along the axon is called ‘Axoplasmic Transport’. It seems that disturbances in axoplasmic transport can cause various neuronal problems. The purpose of this study is to investigate the mechanism of axoplasmic transport and its types; moreover, the possible effect of exercise on this transition will be discussed.

What is already known on this subject?

It seems that disturbances in axoplasmic transport can cause various neuronal problems.


What this study adds?

Some examples of how exercise has a positive effect on regulating axoplasmic transport are provided.


Main Subjects

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