Response of serum C-reactive protein, tumor necrosis factor-α, and heat shock protein 70 levels to trachyspermum copticum and selected swimming training

Document Type : Original Article

Authors

1 Department of Exercise Physiology, Varamin Pishva Branch, Islamic Azad University, Tehran, Iran.

2 MSc of Exercise Physiology, Varamin Pishva Branch, Islamic Azad University, Tehran, Iran.

3 Department Food and Nutrition, Consumer Center of the German Federal State of Bavaria, Munich, Germany.

10.22034/jeoct.2022.340604.1037

Abstract

Regular physical activity is the best defense against many diseases, illnesses, and abnormalities. Aerobic exercise and the consumption of herbal supplements strengthen the body's immune and defense systems. This study aimed to investigate the effect of a period of swimming endurance training with trachyspermum copticum (Ajwain) consumption on serum levels of some inflammatory factors in young men in a randomized clinical trial. The statistical population included all male students less than 25 years of age at the Islamic Azad University of Varamin Phishva, Iran. Among them, sample sizes of 60 people were selected by simple random sampling and were divided into four groups of 15 people each: trachyspermum copticum + training, trachyspermum copticum, training, and control. The training program included endurance swimming for 10 weeks either with or without the addition of trachyspermum copticum. Serum concentrations of tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), and heat shock protein 70 (HSP70) were measured in two-time stages before and after the study period. The level of CRP inflammatory index, TNF-α cytokine, and HSP70 were lower among the training + trachyspermum copticum than in the control group and other experimental groups. Endurance swimming training and trachyspermum copticum with anti-inflammatory properties strengthened the immune system, increased antioxidant defense, and decreased inflammatory markers. Also, the level of physical activity has improved this condition by improving endothelial function.

What is already known on this subject?

The use of trachyspermum copticum and the training method to strengthen the immune system have already been studied alone and other factors and cells of the immune system were examined. Of course, most research has had animal specimens.

 

What this study adds?

In this research, trachyspermum copticum and swimming exercises have been used simultaneously. . Another point is that an acute phase protein, a heat shock protein and an inflammatory cytokine were examined as research variables.

Keywords

Main Subjects


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Volume 2, Issue 2
June 2022
Pages 71-78
  • Receive Date: 04 May 2022
  • Revise Date: 14 June 2022
  • Accept Date: 23 June 2022
  • First Publish Date: 23 June 2022