Journal of Exercise & Organ Cross Talk

Abstract The purpose of this research is to survey the effect of eight weeks of sub-maximal training on the C-Reactive Protein (CRP) in elderly males. The subjects of the research consisted of 21 elderly males between 50-80 years old, divided into two groups (one experimental group and one control group), with VO_2Peak values of 51.14±2.7, 51.92±3.17, and 43.61±1.85 (based on the 1-mile (1609 meters) Track Jog test). The experimental group carried out Balke-Ware sub-maximal aerobic exercise 5 sessions a week for 8 weeks, while the control group did not participate in the training program. The results of the research showed that the average CRP levels decreased in the experimental group, while they increased in the control group. However, these differences were not statistically significant according to the paired sample T-Test results. On the other hand, a significant difference in Vo2 Peak was observed between the two groups (p<0.039 and p<0.001), with the experimental group showing higher values compared to the control group. Additionally, there was no statistically significant difference in HS-CRP levels between the subjects (experimental group 1, experimental group 2, and control group) before and after the training period. In general, it seems that a longer duration is required to observe better markers of inflammatory and cardiovascular effects of these variables. The pre-study hypothesis of cardiorespiratory fitness on CRP response confirms that assessing control and inflammatory markers of cardiorespiratory fitness in the elderly requires more time.

Abstract Intense exercise training is associated with Lung inflammation. Fasl protein on the cell surface is responsible for the initiation of the inflammatory response that finally leads to cell death at the site of inflammation, and can be interpreted as Fasl induced apoptosis. Therefore, the aim of this study was to investigate the effects of increasing and intense interval exercise training on Fasl levels of mature rat lungs. 30 rats within three weeks of birth with mean weight 68±9 g were randomly divided into three basic, control, and exercise groups. Increasing interval training for 6 sessions per week, each session 30 minutes at a speed of 15 to 70 meters per min was employed and Fasl levels were measured using the kitby Elisa method. The data were analyzed with two-way ANOVA and LSD test was done at p≤0.05 significant level. The results showed that Fasl protein levels in the interval training group compared to baseline group increased by 23.75 % and was significant (p≤0/05). However, although the amount of this protein in the interval training group compared to the control group was high, this value was not significant. In addition, Fasl protein levels in the control group compared to the baseline group increased by13.58 % and was significant (p≤0.05). The findings indicated that intense and prolonged exercise training causes damage of the respiratory tract, and in turn, leads to the increased levels of Fasl.